Certified Clinical Research Associate (CCRA) Practice Exam 2025 - Free CCRA Practice Questions and Study Guide

The close-out fees for clinical trials typically encompass various costs that arise once a study is nearing completion. Time spent by site staff reconciling data is a crucial part of the close-out process, as it ensures that all collected data is accurate, complete, and properly documented. During the close-out phase, site staff must carefully review and confirm the data to resolve any discrepancies, making this a significant and necessary activity that contributes to the integrity of the study results.

In contrast, costs associated with patient recruitment and expenses related to regulatory filings are generally incurred during the earlier phases of a clinical trial rather than during the close-out. Similarly, payments for site staff training relate to preparing the staff before the initiation of the study and are not part of the close-out activities.